About the Authors
Foreword: How to Read This Book
1. Introduction: Healthcare Information Synthesis and Informatics
Section A. Fundamental Goals of This Book
Section B. Basic Concepts: 'Information Synthesis' and ' Healthcare Informatics'
Section C. Organization of This Book
Section D. Information Synthesis Methods Literature
Section E. Synthesis Evaluation Criteria
Section F. Potential Contributions of This Book
STAGE I: PLANNING AND PREPARATION
2. Synthese Planning Prerequisites and Conceptual Issues
Section A. Information Synthesis and Resource Constraints
Section B. Informatics and Internet Background
Section C. Alternative Synthesis Designs to Consider
Section D. Formulation of Synthesis Topic and Model
Section E. Synthesis Audience and Their Needs
Section F. Linking Synthesis to Healthcare Outcomes Improvement
Section G. Final Project Planning Issues
3. Procedures for Synthesis Planning and Preparation
Procedure A. Formulate Topic by Group Consensus
Procedure B. Establish a Project Plan
Procedure C. Obtain Informatics Resources
Procedure D. Recruit and Train Project Staff
Procedure E. Organize Project Files
Procedure F. Finalize Preparations
Products of the Procedures in Chapter 3
4. Evaluation and Improvement of Stage I
Procedure A. Assess and Enhance Documentation Adequacy
Procedure B. Assess and Enhance Clinical Significance
Procedure C. Assess and Enhance Scientific Soundness
Procedure D. Assess and Enhance Cost-Effectiveness
STAGE II: DATABASE DEVELOLPMENT
5. Conceptual Issues in Database Development
Section B. Levels of Information Soundness
Section C. Strategic Searth Considerations
Section D. Generic Sources of Halth Science Information
Section E. Fugitive Literature
6. Healthcare Information Search Procedures
Procedure A. Search Prepaation Update
Procedure B. Initial Search Iterations
Procedure C. Subsequent Iterations
Procedure D. Search Termination
7. Evaluation and Improvement of Stage II
Procedure A. Assess and Enhance Documentation Adequacy
Procedure B. Assess and Enhance Clinical Significance
Procedure C. Assess and Enhance Scientific Soundness
Procedure D. Assess and Enhance Cost-Effectiveness
STAGE III: DATABASE VALIDATION
8. Data Extraction and Coding
Section A. Theoretical Issues in Data Extracting and Coding
Section B. Procedures for Extracting and Coding Data
9. Princip0les of Information Validation
Section A. Importance of Validation of Individual Studies
Section B. Causes of Poor Scientific Quality in Published Research
Section C. Analysis of Quantitative Validity
Section D. Analysis of Qualitative Validity
Section E. Use of Validated Information for Synthesis
10. Procedures for Database Validation
Procedure A. Categorize Studies by Research Design
Procedure B. Develop Validation Protocols
Procedure C. Select and Train Reviewers
Procedure D. Calibrate and Standardize Validity Ratings
Procedure E. Validate Literature for Synthesis
11, Evaluation and Improvement of Stage III
Procedure A. Assess and Enhance Validation of Database Documentation Adequacy
Procedure B. Assess and Enhance Validation of Database Clinical Significance
Procedure C. Assess and Enhance Validation of Database Scientific Soundness
Procedure D. Assess and Enhance Validation of Database Cost-Effectiveness
STAGE IV: INFORMATION ANALYSIS AND SYNTHESIS
12. Basic Statistics for Quantitative Synthesis
Section A. Basic Statistical Concepts
Section B. Effect Sizes; Calculation and Use
Section C. Hypothesis Testing in Meta-Analysis
13. Conceptual Aspects of Meta-Analysis
Section A. Designing Multivariate Models
Section B. Selecting Effect Size Index
Section C. Managing Missing Data
Section D. Managing Artifacts and Biases
Section E. Heterogeneity of Effect Sizes Among Studies
Section F. Combining Effect Sizes
Section G. Sensitively Analysis
14. Step-by-Step Procedures for Meta-Analysis
Procedure A. Develop a Strategic Plan
Procedure B. Implement One of Seven Variations of a Meta-Analysis
Procedure C. Conduct a Sensitivity Analysis
15. Evaluation and Improvement of Stage IV Results
Procedure A. Assess and Enhance Documentation Adequacy
Procedure B. Assess and Enhance Clinical Importance
Procedure C. Assess and Enhance Scientific Soundness
Procedure D. Assess and Enhance Cost-Effectiveness
STAGE V: SYNTHESIS REPORT COMPLETION AND EVALUATION
16. Synthesis Manuscript Preparation Primer
Procedure A. Prepare to Write Synthesis Manuscript
Procedure B. Write Body of Synthesis Report
Procedure C. Write Front and Trailing Matter for a Journal Article
Procedure D. Write Front and Trailing Matter for a Book
17. Applying Synthesis Results for Healthcare Outcomes Improvement
Procedure A. Coping With the Difficulty of Behavioral Change and Diffusion of Innovation
Procedure B. Avoiding Conflicts of Interest and Hazards of Science Propaganda
Procedure C. Achieving Healthcare Outcomes Improvement
18. Evaluation and Refinement of Synthesis Report
Procedure A. Understanding Considerations for Project Finalization
Procedure B. Finalizaing the Synthesis Project
Procedure C. Self-Assessing the Final Synthesis
Procedure D. Has Your Final Product Been Worth the Effort and Cost Involved?
Glossary
References
Index
Synopsis of Compendium